ABSTRACT
Objective To investigate the effect of Fukeqianjin tablets combined with progesterone on serum immunoglobulin,serum IL-2 and soluble receptor levels in patients with functional uterine bleeding,and to explore the optimal regimen for patients with functional uterine bleeding.Methods A total of 98 patients with functional uterine bleeding diagnosed in our hospital from June,2015 to June,2016 were randomLy divided into observation group and control group(n=49).The patients in the control group were treated with oral progesterone and the observation group.The control group was treated on the basis of the combination of gynecological Qianjin Tablet,compared the two groups of patients before and after treatment of menstrual conditions,serum IgM,IgA,serum IL-2 and soluble receptor levels.Results In the first month,the second month and the third month after treatment,the menstrual volume in the observation group were(103.5±21.5)mL,(93.5±14.7)mL,(81.4± 12.2)(7.68±0.92)d,(6.81±0.87)d and(6.14±0.78)d respectively in the observation group were significantly shorter than those in the control group(P<0.05).After treatment,the menstrual period The serum levels of IgA and IgM were(3.6±0.8),(2.6±0.8),(1.8±0.3)and(2.9±0.5),(2.2±0.3),(1.1±0.2)in the first month,the second month and the third month respectively,Significantly lower than the control group,the difference was statistically significant; the first month after treatment,the first two months,the first three months,observation group of patients with serum IL-2 and soluble receptor levels significantly Lower than the control group.Conclusion Fukeqianjin tablets combined with progesterone can improve the immune function of patients with functional uterine bleeding,reduce the level of inflammation and soluble receptor levels,compared with single progesterone treatment better,the program better.
ABSTRACT
Objective To analyze the therapeutic effect of oxaliplatin combined with tegafur on the treatment of gastric cancer patients after operation.Methods A retrospective analysis was used to analysis the clinical dated of gastric cancer patients received radical surgery in the First Affiliated Hospital of Xiamen University from April 2012 to August 2014, according to the surgical treatment of the postoperative adjuvant chemotherapy, which were divided into oxaliplatin combined with tegafur group and oxaliplatin combined with tegafur group.The lymph nodes and survival rate and recurrence rate of the two groups were observed after two years.The quality of life and the incidence of complications in the two groups were evaluated. Results The two years recurrence and metastasis rate of Oxaliplatin combined with tegafur group were lower than mFolfox6 program group (P<0.05);the one year survival rate was no difference of oxaliplatin combined with tegafur group two years survival rate is higher than that of mFolfox6 group, the rate of nausea and vomiting, leukopenia and urea nitrogen in oxaliplatin combined with tegafur group were higher ( P <0.05 ).Physical function, physical role, limb pain and other quality of life score of the two groups had no significant difference before treatment, after treatment, the indea of oxaliplatin combined with tegafur group was lower than mFolfox6 program group ( P <0.05 ) .Conclusion Oxaliplatin combined with tegafur can significantly reduce the rate of recurrence and metastasis of gastric cancer patients after operation, and improve the quality of life of patients after operation.